発生生物学です
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A model of anterior-posterior pattern generation by the Drosophila maternal effect genes.(A) The bicoid, nanos, hunchback, and caudal messnger RNAs are placed in the oocyte by the ovarian nurse cells.
The bicoid messenger is sequestered anteriorly.
The nanos messenger is sent to the posterior pole.
(B) upon translation, the Bocoid protein gradient extends from anterior to posterior, and the Nanos protein gradient extends from posterior to anterior.Nanos inhabits the translation of the hunchback message (in the posterior), while Bicoid prevents the translation of the caudal message(in the anterior).This inhibition results in opposing Caudal and Hunchback gradients.The Hunchback gradient is secondarily strengthened by the transcription of the hunchback gene in the anterior nuclei(since Bicoid acts as a transcription factor to activate hunchback transcription).
(C)Parallel interactions whereby translational gene regulation establishes the anterior-posterior patterning of the Drosophila embryo.
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